Tracking human face features in thermal images for respiration monitoring

A method has been developed to track a region related to respiration process in thermal images. The respiration region of interest (ROI) consisted of the skin area around the tip of the nose. The method was then used as part of a non-contact respiration rate monitoring that determined the skin temperature changes caused by respiration. The ROI was located by the first determining the relevant salient features of the human face physiology. These features were the warmest and coldest facial points. The tracking method was tested on thermal video images containing no head movements, small random and regular head movements. The method proved valuable for tracking the ROI in all these head movement types. It was also possible to use this tracking method to monitor respiration rate involving a number of head movement types. Currently, more investigations are underway to improve the tracking method so that it can track the ROI in cases larger head movements

The Effectiveness of Using Response- based Strategy in Enhancing Students' Levels of Engagement, Motivation, Problem-solving Skills, and Critical Thinking

The study analyzed the efficacy of response-based teaching tactics in enhancing students' levels of engagement, motivation, problem-solving skills, and critical thinking by utilizing data and a mixed-methods research methodology. There was a total of 30 students in the sample, 15 of whom were assigned to each of the two groups (response-based techniques and conventional instruction). Researchers also looked at how factors like teacher background and technological sophistication influenced the success of these techniques in the classroom. The students participated in a pre-test to define a starting point and a post-test to evaluate growth throughout the study. The efficacy of the response-based tactics was determined by statistical analysis using t-tests, ANOVA, and Cohen's d. Teacher and student demographics, as well as information about classroom practises and the usage of technology, were gathered through an online survey. Student perceptions of their own problem-solving and critical-thinking skills, as well as their level of classroom participation and motivation, were also probed in the survey. Both quantitative and qualitative approaches were employed to gather and analyze the data for this study. In terms of improving students' interest, motivation, problem-solving skills, and critical thinking, the results demonstrated that response-based teaching tactics were superior to more conventional methods. However, it was discovered that teacher traits and technology use influenced the efficacy of the response-based tactics. The findings also suggested that response-based teaching tactics might be useful in online classrooms, with the caveat that the success of such strategies would depend on the specific nature of the strategies employed and the specific features of the technology tools used. Conclusions from the study indicate that using response-based teaching methodologies can improve students' interest, motivation, problem-solving skills, and critical-thinking capacities. This study's methodology and statistical methods can serve as a foundation for other studies in this field. Keywords: response-based teaching strategies, traditional teaching approaches, student engagement, student motivation, problem-solving skills, critical thinking abilities DOI: 10.7176/JEP/14-27-10 Publication date:September 30th 2023

A Novel Digital Signature Scheme for Advanced Asymmetric Encryption Techniques

Digital signature schemes are practical mechanisms for achieving message integrity, authenticity, and non-repudiation. Several asymmetric encryption techniques have been proposed in the literature, each with its proper limitations. RSA and El Gamal prove their robustness, but are unsuitable in several domains due to their computational complexity. Other asymmetric encryption schemes have been proposed to provide a cloud homomorphic encryption service, where the researchers focused only on how to ensure the homomorphic property. This paper proposes a new digital signature scheme dedicated to a family of encryption techniques. The proposal consists of two parts: the first focused on the secret key, and the second focused on the public key. Signature validity checking was performed by multiplying these two parts to reform again the sender’s public key, then comparing the result with the decrypted message. The validation of the decrypted message guarantees data integrity, where the signer public key is used to ensure authenticity. The proposed scheme takes a shorter execution time for the entire signature operation, including signing and verification, compared to other modern techniques. The analysis showed its robustness against private key recovery and forgery attacks. The implementation results of the proposed scheme showed promising performance in terms of complexity and robustness. The results confirmed that the proposed scheme is efficient and effective for signature generation and verification

Resonant tunneling diode photodetectors for optical communications

Resonant tunneling diodes (RTDs) have been extensively studied due to their potential applications in very high speed electronics, optical communications, and terahertz generation. In this work, we report the latest results on the characterization of the resonant tunneling diode photo-detectors (RTD-PDs), incorporating InGaAlAs light sensitive layers for sensing at the telecommunication wavelength of lambda = 1310 nm. We have measured responsivities up to 28.8 A/W and light induced voltage shift of 204.8 V/W for light injection powers around 0.25 mW.Fundacao para a Ciencia e a Tecnologia (FCT) [UID/Multi/00631/2013]; European Structural and Investment Funds (FEEI) through the Competitiveness and Internationalization Operational Program (COMPETE); FCT [ALG-01-0145-FEDER-016432/POCI-01-0145-FEDER-016432]; European Commission under the project iBROW [645369

Presence of mechanical dyssynchrony in duchenne muscular dystrophy

<p>Abstract</p> <p>Background</p> <p>Cardiac dysfunction in boys with Duchenne muscular dystrophy (DMD) is a leading cause of death. Cardiac resynchronization therapy (CRT) has been shown to dramatically decrease mortality in eligible adult population with congestive heart failure. We hypothesized that mechanical dyssynchrony is present in DMD patients and that cardiovascular magnetic resonance (CMR) may predict CRT efficacy.</p> <p>Methods</p> <p>DMD patients (n = 236) were stratified into 4 groups based on age, diagnosis of DMD, left ventricular (LV) ejection fraction (EF), and presence of myocardial fibrosis defined as positive late gadolinum enhancement (LGE) compared to normal controls (n = 77). Dyssynchrony indices were calculated based on timing of CMR derived circumferential strain (e_cc). The calculated indices included cross-correlation delay (XCD), uniformity of strain (US), regional vector of variance (RVV), time to maximum strain (TTMS) and standard deviation (SD) of TTMS. Abnormal XCD value was defined as > normal + 2SD. US, RVV, TTMS and SD were calculated for patients with abnormal XCD.</p> <p>Results</p> <p>There was overall low prevalence of circumferential dyssynchrony in the entire DMD population; it increased to 17.1% for patients with abnormal EF and to 31.2% in the most advanced stage (abnormal EF with fibrosis). All but one DMD patient with mechanical dyssynchrony exhibited normal QRS duration suggesting absence of electrical dyssynchrony. The calculated US and RVV values (0.91 ± 0.09, 1.34 ± 0.48) indicate disperse rather than clustered dyssynchrony.</p> <p>Conclusion</p> <p>Mechanical dyssynchrony is frequent in boys with end stage DMD-associated cardiac dysfunction. It is associated with normal QRS complex as well as extensive lateral fibrosis. Based on these findings, it is unlikely that this patient population will benefit from CRT.</p

Development of high-resolution infrared thermographic imaging method as a diagnostic tool for acute undifferentiated limp in young children

Acute limp is a common presenting condition in the paediatric emergency department. There are a number of causes of acute limp that include traumatic injury, infection and malignancy. These causes in young children are not easily distinguished. In this pilot study, an infrared thermographic imaging technique to diagnose acute undifferentiated limp in young children was developed. Following required ethics approval, 30 children (mean age = 5.2 years, standard deviation = 3.3 years) were recruited. The exposed lower limbs of participants were imaged using a high-resolution thermal camera. Using predefined regions of interest (ROI), any skin surface temperature difference between the healthy and affected legs was statistically analysed, with the aim of identifying limp. In all examined ROIs, the median skin surface temperature for the affected limb was higher than that of the healthy limb. The small sample size recruited for each group, however, meant that the statistical tests of significant difference need to be interpreted in this context. Thermal imaging showed potential in helping with the diagnosis of acute limp in children. Repeating a similar study with a larger sample size will be beneficial to establish reproducibility of the results

Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial

Importance: Adoption of guideline-directed medical therapy for patients with heart failure is variable. Interventions to improve guideline-directed medical therapy have failed to consistently achieve target metrics, and limited data exist to inform efforts to improve heart failure quality of care. Objective: To evaluate the effect of a hospital and postdischarge quality improvement intervention compared with usual care on heart failure outcomes and care. Design, Setting, and Participants: This cluster randomized clinical trial was conducted at 161 US hospitals and included 5647 patients (2675 intervention vs 2972 usual care) followed up after a hospital discharge for acute heart failure with reduced ejection fraction (HFrEF). The trial was performed from 2017 to 2020, and the date of final follow-up was August 31, 2020. Interventions: Hospitals (n = 82) randomized to a hospital and postdischarge quality improvement intervention received regular education of clinicians by a trained group of heart failure and quality improvement experts and audit and feedback on heart failure process measures (eg, use of guideline-directed medical therapy for HFrEF) and outcomes. Hospitals (n = 79) randomized to usual care received access to a generalized heart failure education website. Main Outcomes and Measures: The coprimary outcomes were a composite of first heart failure rehospitalization or all-cause mortality and change in an opportunity-based composite score for heart failure quality (percentage of recommendations followed). Results: Among 5647 patients (mean age, 63 years; 33% women; 38% Black; 87% chronic heart failure; 49% recent heart failure hospitalization), vital status was known for 5636 (99.8%). Heart failure rehospitalization or all-cause mortality occurred in 38.6% in the intervention group vs 39.2% in usual care (adjusted hazard ratio, 0.92 [95% CI, 0.81 to 1.05). The baseline quality-of-care score was 42.1% vs 45.5%, respectively, and the change from baseline to follow-up was 2.3% vs -1.0% (difference, 3.3% [95% CI, -0.8% to 7.3%]), with no significant difference between the 2 groups in the odds of achieving a higher composite quality score at last follow-up (adjusted odds ratio, 1.06 [95% CI, 0.93 to 1.21]). Conclusions and Relevance: Among patients with HFrEF in hospitals randomized to a hospital and postdischarge quality improvement intervention vs usual care, there was no significant difference in time to first heart failure rehospitalization or death, or in change in a composite heart failure quality-of-care score. Trial Registration: ClinicalTrials.gov Identifier: NCT03035474

Autoimmune enteropathy with a CD8+ CD7- T-cell small bowel intraepithelial lymphocytosis: case report and literature review

<p>Abstract</p> <p>Background</p> <p>Adult onset autoimmune enteropathy (AIE) is a rare condition characterized by diarrhea refractory to dietary therapy diagnosed in patients with evidence of autoimmune conditions. Auto-antibodies to gut epithelial cells and other tissues are commonly demonstrated. Despite increasing awareness, the pathogenesis, histologic, immunologic and clinical features of AIE remain uncertain. There remains controversy regarding the diagnostic criteria, the frequency and types of auto-antibodies and associated autoimmune conditions, and the extent and types of histologic and immunologic abnormalities. CD4+ T-cells are thought to at least responsible for this condition; whether other cell types, including B- and other T-cell subsets are involved, are uncertain. We present a unique case of AIE associated with a CD8+CD7- lymphocytosis and review the literature to characterize the histologic and immunologic abnormalities, and the autoantibodies and autoimmune conditions associated with AIE.</p> <p>Case Presentation</p> <p>We present a case of immune mediated enteropathy distinguished by the CD8+CD7- intra-epithelial and lamina propria lymphocytosis. Twenty-nine cases of AIE have been reported. The majority of patients had auto-antibodies (typically anti-enterocyte), preferential small bowel involvement, and predominately CD3+ CD4+ infiltrates. Common therapies included steroids or immuno-suppressive agents and clinical response with associated with histologic improvement.</p> <p>Conclusions</p> <p>AIE is most often characterized (1) IgG subclass anti-epithelial cell antibodies, (2) preferential small bowel involvement, and (3) CD3+ alphabeta TCR+ infiltrates; there is insufficient evidence to conclude CD4+ T-cells are solely responsible in all cases of AIE.</p

Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes

Rare mitochondrial lineages with relict distributions can sometimes be disproportionately informative about deep events in human prehistory. We have studied one such lineage, haplogroup R0a, which uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, from Europe to India. We conclude that: (1) the lineage ancestral to R0a is more ancient than previously thought, with a relict distribution across the Mediterranean/Southwest Asia; (2) R0a has a much deeper presence in Arabia than previously thought, highlighting the role of at least one Pleistocene glacial refugium, perhaps on the Red Sea plains; (3) the main episode of dispersal into Eastern Africa, at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions from one or more refugia in Arabia; (4) there was likely a minor Late Glacial/early postglacial dispersal from Arabia through the Levant and into Europe, possibly alongside other lineages from a Levantine refugium; and (5) the presence of R0a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ~3 ka between Africa and the Indian Ocean led to some gene flow even further afield, into Iran, Pakistan and India